A condition that is caused by excessive secretion of the thyroid glands which raises the basal metabolic rate causing an increased demand for food to support the metabolic activity. Symptoms include goiter, a fine tremor of the extended fingers and tongue, increased nervousness, weight loss, altered bowel activity, excessive sweating and increased heart rate.

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A condition that is due to deficiency of the thyroid secretion which results in a lowered basal metabolism. Symptoms include obesity, low blood pressure, slow pulse, sluggishness of all functions, depressed motor activity and dry skin and hair, both of which become dull.

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Any of a variety of rare pathological conditions that affect fewer than one in 2,000 individuals. Orphan diseases are further defined as those whose occurrence is so rare that research regarding treatment has not been a priority, or the disease lacks research and treatment options.

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